GONORRHOEA – MANAGEMENT (PENICILLIN RESISTANT INFECTION)
Monday, October 11th, 2010Patients, except pregnant females, who are sensitive to penicillin can be treated with spectinomycin (see below), tetracyclines or trimethoprim/sulphamethoxazole. Pregnant patients should be treated with erythromycin.
Penicillin resistant infection (first line treatment where PPNG is endemic) Adults:
Ceftriaxone 250 mg intramuscularly in a single dose OR
Spectinomycin 2 g intramuscularly in a single dose. (Spectinomycin should not be used in pregnancy)
Children:
Spectinomycin 40 mg/kg intramuscularly in a single dose.
Complicated infections (PID, septic arthritis, septicaemia etc.)
Complicated infections such as PID, prostatitis or epididymitis, arthritis, ophthalmic lesions, disseminated infection, meningitis, endocarditis, myocarditis or pericarditis require multiple dose therapy. Hospitalisation and specialist referral is usually indicated. These patients often require intravenous chemotherapy which is replaced by oral treatment on clinical improvement. Duration of treatment will be at least 7 days extended to at least 14 days for meningitis and at least a month for endocarditis.
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